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Since its establishment in 1920, Hellenic Pasteur Institute (HPI) remains faithful to its mission, which is the prevention and treatment of Diseases through Basic Research, Education and Public Health Services. The traditional focus of the Institute has been on Infectious Diseases.

Currently other diseases are also under study such as autoimmune, neurodegenerative, neuromuscular, neuroimmune and certain types of cancer.

The Hellenic Pasteur Institute (HPI) is a private, non-profit organization supervised by the Ministry of Education, Lifelong Learning and Religious Affairs and the Ministry of Health and Social Solidarity and is functioning under the Greek law concerning Research Centres and a Bilateral Agreement between the Greek Government and the Pasteur Institute in Paris.

HPI, is a member of the International Network of Pasteur Institutes and maintains strong collaborations with the Pasteur Institute in Paris and other Institutes of the Network in North and Central Africa, SE Asia, Europe and Canada.